Hepatosplenic and Hepatocytotropic T-Cell Lymphoma
نویسندگان
چکیده
منابع مشابه
Hepatosplenic T-cell lymphoma: A case series.
Hepatosplenic T-cell lymphoma (HSTCL) is a rare type of Non-Hodgkin Lymphoma (NHL), grouped under the mature or peripheral T-cell lymphomas. It is characterised by extranodal infiltration and proliferation of malignant T-cells within the sinusoids of the liver, sinuses and red pulp of the spleen, and the bone marrow. The tumour cells express CD2 and CD3, but are CD4, CD5 and CD8 negative and ex...
متن کاملLiterature Review : Hepatosplenic T - cell Lymphoma
Hepatosplenic T-cell lymphoma (HSTCL) is a rare type of T-cell lymphoma with poor clinical outcomes. Typical clinical features include a predominance of young male with fever, hepatosplenomegaly and cytopenia with the absence of appreciable lymphadenopathy. Diagnosis is based on examination of peripheral blood and histopathology of bone marrow, spleen or liver. In addition, immunophenotyping an...
متن کاملChallenges and new prospects in hepatosplenic γδ T-cell lymphoma.
Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of lymphoid neoplasms characterized by aggressive clinical behavior and dismal prognosis. Hepatosplenic γδ T-cell lymphoma (γδ-HSTL) is a particular form of PTCL that arises from a small subset of γ/δ T-cell receptor-expressing lymphocytes. γδ-HSTL has a rapidly progressive course and poor outcome due also to its refractoriness to co...
متن کاملHepatosplenic T-cell lymphoma appearing in the peripheral blood.
A previously healthy 23-year-old Japanese male had complained of a fever lasting a month. A physical examination revealed marked hepatosplenomegaly without significant peripheral lymphadenopathies. Routine laboratory tests showed a hemoglobin level of 9.1 g/dL, 95 3 10/L platelets, 7.1 3 10/L leukocytes, and an elevated lactate dehydrogenase level of 522 U/L (reference interval, 120-220 U/L). A...
متن کاملHepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease.
Tumour necrosis factor inhibitors have revolutionised the management of Crohn's disease, but reports of a possible association between concomitant infliximab and immunomodulator therapy and hepatosplenic T-cell lymphoma (a rare form of aggressive non-Hodgkin's lymphoma) have emerged. We describe the first case in Australia of hepatosplenic T-cell lymphoma in a patient who had been treated with ...
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ژورنال
عنوان ژورنال: Veterinary Pathology
سال: 2012
ISSN: 0300-9858,1544-2217
DOI: 10.1177/0300985812451625